loess normalization

Source: R/utilities.R

loess normalization

normalize.loess(
  mat,
  subset = sample(seq.int(nrow(mat)), min(c(5000, nrow(mat)))),
  span = 2/3,
  family.loess = "symmetric"
)

Arguments

mat

a matrix with columns containing the values of the chips to normalize.

subset

a subset of the data to fit a loess to.

span, family.loess

parameter to be passed the function loess.

Value

the mean matrix to be subtracted.